Regulation of Trichophyton rubrum proteolytic activity

Regulation of Trichophyton rubrum proteolytic activity.

Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation of these enzymes and their role in fungal metabolism were studied at the biochemical level. General proteolytic (azocollytic)...

In vitro Antifungal Activity of Limonene against Trichophyton rubrum

In this study, the antifungal activities of limonene against Trichophyton rubrum were evaluated via broth microdilution and vapor contact assays. In both assays, limonene was shown to exert a potent antifungal effect against T. rubrum. The volatile vapor of limonene at concentrations above 1 µl/800 ml air space strongly inhibited the growth of T. rubrum. The MIC value was 0.5% v/v in the broth ...

Differentiation of Trichophyton Rubrum and Trichophyton Mentagrophytes by Pigment Production.

Trichophyton rubrum infection of the prepuce.

Sir, Dermatophyte infection of the penis and scrotum is rare. It is difficult to explain why the penile shaft is generally not involved in patients affected by tinea cruris. Glans penis involvement is considered even rarer, whereas dermatophytosis of the prepuce has not been reported in the literature. Here we report a patient who presented with scaly lesion on the prepuce, which on investigati...

Factors affecting the antigenicity of Trichophyton rubrum.

Nitrogen determinations, performed upon the mycelia of Trichophyton rubrum, indicated that both the total nitrogen to mycelial weight ratio and the protein nitrogen to mycelial weight ratio decreased as the age of the mycelia increased. An increase in nitrogen concentration in the medium produced an increase in the total nitrogen to mycelia weight ratio, but did not necessarily increase the pro...